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The following is a summary of “Clinical-radiomics combination model for predicting the short-term efficacy of bipolar transurethral enucleation of the prostate in patients with benign prostatic hyperplasia” published in the September 2024 issue of Urology by Zhang  et al. 

Bipolar transurethral enucleation of the prostate (B-TUEP) is a common treatment for benign prostatic hyperplasia (BPH). Magnetic resonance imaging with radiomics analysis provides detailed insights into prostate characteristics that may influence surgical outcomes. 

Researchers conducted a retrospective study to assess the value of MRI and radiomics in predicting the short-term efficacy of B-TUEP for BPH.  

They included 137 patients with BPH who underwent B-TUEP across two institutions. Radiological features were measured from MRI, and a radiomics score was developed from 1,702 features extracted from the prostate and transitional zone. Then, 3 prediction models were developed based on clinical-radiological features, radiomic features, and their combinations. Model performance was evaluated using the area under the receiver operating characteristic curve, calibration curve, and decision curve analysis. 

The results showed that the combination model had the highest area under the curve in both the training set (0.838) and external validation set (0.802), indicating superior performance. It also demonstrated good calibration (P > 0.05) and optimal clinical utility. Higher maximum urine flow rate, lower transitional zone index, and higher radiomics score were associated with poorer efficacy. 

They concluded that MRI with radiomic analysis predicted the short-term efficacy of B-TUEP in patients with BPH. The combination model aided in making more precise clinical decisions. 

Source: journals.lww.com/cur/fulltext/9900/clinical_radiomics_combination_model_for.170.aspx