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The following is a summary of “Relationship between neuropathic pain and lower urinary tract symptom scores in patients with primary Sjögren’s syndrome,” published in the November 2024 issue of Urology by Erdik et al. 

Researchers conducted a retrospective study to evaluate the effect of neuropathic pain on lower urinary tract symptoms (LUTS) scores in patients with primary Sjögren’s syndrome (pSS).  

They included 72 patients diagnosed with pSS, divided into two groups based on the presence or absence of neuropathic pain. They assessed neuropathic pain using the Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) questionnaire. They evaluated LUTS using the International Prostate Symptom Score (IPSS), International Incontinence Consultation Questionnaire Short Form (ICIQ-SF), and Overactive Bladder Questionnaire (OAB-V8). 

The results showed that the mean age of the patients was 52.4 ± 11.2 years, with 21 (29.2%) having neuropathic pain. About 41 (56.9%) were recorded as mild symptoms, moderate symptoms in 25 (34.7%), and severe symptoms in 6 (8.3%) according to IPSSIPSS and IPSS voiding subscores were significantly higher in the neuropathic pain group (P = 0.035; P = 0.001). The groups had no significant differences in ICIQ-SF, OAB-V8, or IPSS storage subscores (P = 0.299; P = 0.283; P = 0.237). 

Investigators found that neuropathic pain in patients with PSS negatively affected bladder voiding functions. 

Source: bmcurol.biomedcentral.com/articles/10.1186/s12894-024-01650-1