Faecal haemoglobin concentrations associated with mortality and cause of death in colorectal cancer screening
1. In this prospective cohort study, fecal hemoglobin concentration (f-Hb) was associated with...
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Oncology
Adjuvant S-1 increases short-term survival in patients with resected biliary tract cancer
1. Patients who received adjuvant S-1 had prolonged overall survival and relapse-free survival...
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Plant-based diets may be associated with lower risk of aggressive prostate cancer
1. In this prospective cohort study, greater consumption of healthful plant-based foods was...
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Machine-learning based prompts for serious illness conversations reduces end of life systemic therapy use
1. The proportion of patients receiving serious illness conversations (SICs) was increased in the...
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Futibatinib for FGFR2 Mutated Intrahepatic Cholangiocarcinoma
1. Using futibatinib to treat patients with FGFR mutated intrahepatic cholangiocarcinoma resulted...
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Adagrasib provides antitumour activity against KRAS G12C mutant metastatic colorectal cancer both as monotherapy and in combination with cetuximab
1. Overall tumour response to monotherapy treatment with adagrasib was 23% 46% in combination with...
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Cisplatin with Veliparib in BRCA Stratified Metastatic Triple-Negative Breast Cancer
1. There was some progression-free survival benefit in adding veliparib to cisplatin in patients...
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Early-life body size not an independent risk factor for colorectal cancer
1. Greater early-life body size is not an independent risk factor for colorectal cancer (aside...
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Spiritual care reduces fatigue and pain among patients receiving chemotherapy
1. In this randomized controlled trial, the post-test fatigue score was significantly lower in...
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Religious-based interventions improve illness perception in breast cancer patients
1. In this randomized controlled trial, religious psychotherapy was associated with significant...
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Sotorasib in KRAS p.G12C–Mutated Advanced Pancreatic Cancer
1. In patients with KRAS p.G12C mutated pancreatic cancer, 21% had a partial response, and 0% had...
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Characterization of prognostic markers of residual neoplastic disease following hysterectomy
1. Prognostic markers of residual disease following a loop electrosurgical excision procedure for...
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Direct-acting antiviral agents significantly lower Hepatitis C related mortality and cancer risk
1. In this retrospective cohort study, adult patients with hepatitis C virus (HCV) infection...
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Tumor-infiltrating lymphocyte therapy compared to ipilimumab in advanced melanoma
1 .Tumor-infiltrating lymphocytes therapy shows improvements in PFS when compared to ipilimumab 2....
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Positive prostate MRI and targeted biopsy reduce the detection of clinically insignificant prostate cancer
1. Fewer instances of clinically insignificant prostate cancer were identified in an experimental...
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PD-1 antibody plus chemotherapy in low PD-L1 expressing esophageal squamous cell carcinoma
1. The post-hoc analysis of JUPITER-06 showed the superiority of adding toripalimab (PD-1...
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The majority of FDA-approved drug trials recruit from low- and middle-income countries
1. This study found that a high proportion of Food and Drug Administration (FDA) drug trials...
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Overall survival with triplet therapy in BRAF V600 mutation-positive advanced melanoma
1. OS in triplet combination therapy (atezolizumab, vemurafenib, and cobimetinib) while numerally...
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Autologous tumour lysate-loaded dendritic cell vaccine in conjunction with standard treatment for glioblastoma may increase overall survival
1. Patients receiving autologous tumour lysate-loaded dendritic cell vaccine (DCVax-L) had a 20%...
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Preoperative biliary draining prior to pancreaticoduodenectomy not associated with increased complication risk
1. In patients with a pancreatic or periampullary tumour undergoing pancreaticoduodenectomy (PD),...
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