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OB/GYN General

Multi-maintenance olaparib therapy in relapsed, germline BRCA1/2-mutant high-grade serous ovarian cancer (MOLTO): a phase II trial.

Feb 20, 2023

A single maintenance course of a poly(ADP-ribose) polymerase inhibitor (PARPi) improves progression-free survival (PFS) in germline BRCA1/2-mutant high-grade serous ovarian cancer (gBRCAm-HGSOC). The ...

Association of endometriosis with cardiovascular disease: Genetic aspects (Review).

Feb 20, 2023

Cardiovascular disease (CVD) comprises a broad spectrum of pathological conditions that affect the heart or blood vessels, including sequelae that arise from damaged vasculature in other organs of the...

Screening and identification of hub-gene associated with brain metastasis in breast cancer.

Feb 20, 2023

The presence of breast cancer in the brain, also known as brain metastasis (BMS), is the primary reason for a bad prognosis in cases of breast cancer. Breast cancer is the most prevalent malignant tum...

Understanding factors that influence whether a woman will seek care for reproductive health: A national survey.

Feb 20, 2023

A number of studies have characterized the importance of regular OB/GYN visits for women who are above the age of 18. As more emphasis is placed on reproductive healthcare, there has been an overall d...

Deep learning for the ovarian lesion localization and discrimination between borderline and malignant ovarian tumors based on routine MR imaging.

Feb 20, 2023

To establish a deep learning (DL) model in differentiating borderline ovarian tumor (BOT) from epithelial ovarian cancer (EOC) on conventional MR imaging. We retrospectively enrolled 201 patients of 1...

Implications for COVID-19 Practice Regarding Semen Parameters and Fertility Outcomes

Feb 17, 2023

The following is a summary of "Effect of semen collection location on semen parameters and fertility outcomes and implications for practice in the COVID-19 era: a systematic review and meta-analysis o...

Maternal Blood cfDNA and AI: Accurate Prenatal Diagnosis of Fetal CHD

Feb 16, 2023

The following is a summary of "Cell-free DNA in maternal blood and artificial intelligence: accurate prenatal detection of fetal congenital heart defects," published in the January 2023 issue of Obste...

Analyzing Features of Molecular Luteal and IVF in Cancer Patients

Feb 15, 2023

The following is the summary of “IVF characteristics and the molecular luteal features of random start IVF cycles are not different from conventional cycles in cancer patients” published in the Ja...

LH Enhances the FSH Response in hGLC from Sub/poor-responder Women in Vitro

Feb 14, 2023

The following is the summary of “LH increases the response to FSH in granulosa-lutein cells from sub/poor-responder patients in vitro” published in the January 2023 issue of Human reproduction by ...

Diagnozing Malignant or Benign Extra-ovarian Condition During Ovarian Follicle Pool Decline

Feb 13, 2023

The following is the summary of “Role of apoptosis and autophagy in ovarian follicle pool decline in children and women diagnosed with benign or malignant extra-ovarian conditions” published in th...

Prevalence of pelvic floor disorders in the Eastern Mediterranean region: A meta-analysis.

Feb 13, 2023

High prevalence of risk factors for pelvic floor disorders (PFD) in the Eastern Mediterranean may result in higher rates of prevalence of PFD in comparison to other regions. Despite individual studies...

Intention matters: Success rate of bilateral salpingo-oophorectomy at the time of vaginal hysterectomy for pelvic organ prolapse.

Feb 13, 2023

The objective of this study was to determine the incidence of successful bilateral salpingo-oophorectomy at the time of vaginal hysterectomy for pelvic organ prolapse and to evaluate associated factor...

Investigating Genetic Determinants of Plasma Inositol Status in Adult Humans.

Feb 13, 2023

Myo-inositol (MI) is incorporated into numerous biomolecules, including phosphoinositides and inositol phosphates. Disturbance of inositol availability or metabolism is associated with various disorde...

Epigenetic alterations impede epithelial-mesenchymal transition by modulating centrosome amplification and Myc/RAS axis in triple negative breast cancer cells.

Feb 13, 2023

Alterations in centrosome proteins may result in centrosome abnormalities such as disorganized spindles and centrosome amplification, leading to aneuploidy and genomic instability. Centrosomes exhibit...

Psychological distress and decision-making factors for prophylactic bilateral mastectomy in cancer-unaffected BRCA1/2 pathogenic variant carriers.

Feb 13, 2023

Women carrying a BRCA1/2 pathogenic variant have increased risk for breast cancer and may opt for risk-reducing bilateral mastectomy. In this study, we examine which demographic, psychosocial, and per...

Evaluation and Management of Early Pregnancy: A Flipped Classroom Case for OB/GYN Clerkship Students.

Feb 13, 2023

Evaluation and management of an early pregnancy diagnosis are clinically pertinent to multiple specialties that will encounter reproductive-age patients. We designed an interactive, small-group, flipp...

Learning Curve for Ultrasound Assessment of Myometrial Infiltration in Endometrial Cancer Visualizing Videoclips: Potential Implications for Training.

Feb 13, 2023

Diagnostic accuracy for estimating myometrial infiltration by ultrasound in endometrial cancer requires experience. The objective of this study is to determine the learning curve (LC) for assessing my...

Analyzing Outcomes Following ART’s in Women Suffering from Cancer

Feb 10, 2023

The following is the summary of “Outcomes after assisted reproductive technology in women with cancer: a systematic review and meta-analysis” published in the January 2023 issue of Human Reproduct...

Spontaneous Preterm Birth: Evaluating Placental Transcriptomic Signatures

Feb 09, 2023

The following is a summary of "Placental transcriptomic signatures of spontaneous preterm birth," published in the January 2023 issue of Obstetrics and Gynecology by Paquette, et al. Most prete...

Weight Loss and Reduced Fetal Growth Velocity with Adverse Perinatal Outcomes in Growth Restricted Fetuses

Feb 08, 2023

The following is a summary of "Reduced fetal growth velocity and weight loss are associated with adverse perinatal outcome in fetuses at risk of growth restriction," published in the January 2023 issu...

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