PubMed

The EMBO journal 11(11) 3887-95 Abstract The classical type of programmed cell death is characterized by its dependence on de novo RNA and protein synthesis and morphological features of apoptosis. We confirmed that stimulated...

Cancer 2012 04 27118(22) 5623-9 doi 10.1002/cncr.27598 Abstract BACKGROUND Completion of the human papillomavirus (HPV) vaccine in a large percentage of young females is an important goal to prevent anogenital cancers associated...

Journal of internal medicine 2012 05 24272(5) 514-5; author reply 516 doi 10.1111/j.1365-2796.2012.02551.x Abstract

Molecular cell 2018 09 21() pii 10.1016/j.molcel.2018.08.020 Abstract Double-strand breaks (DSBs) are extremely detrimental DNA lesions that can lead to cancer-driving mutations and translocations. Non-homologous end joining...

Nature communications 2018 07 189(1) 2794 doi 10.1038/s41467-018-05273-7 Abstract Mutations in proteins like FUS which cause Amyotrophic Lateral Sclerosis (ALS) result in the aberrant formation of stress granules while...

Bone & joint research 6(7) 399-404 doi 10.1302/2046-3758.67.BJR.2016-0255.R1 Abstract OBJECTIVES The injured anterior cruciate ligament (ACL) is thought to exhibit an impaired healing response, and attempts at surgical...

Nature communications 2018 07 179(1) 2777 doi 10.1038/s41467-018-05245-x Abstract Cas12a (also called Cpf1) is a representative type V-A CRISPR effector RNA-guided DNA endonuclease, which provides an alternative to type II...

Cell reports 24(3) 538-545 pii 10.1016/j.celrep.2018.06.061 Abstract RAD51 promotes homologous recombination repair (HR) of double-strand breaks and acts during DNA replication to facilitate fork reversal and protect nascent DNA...

The New England journal of medicine 2018 07 18() doi 10.1056/NEJMoa1806842 Abstract Background Concern about the use of epinephrine as a treatment for out-of-hospital cardiac arrest led the International Liaison Committee on...

eLife 2018 07 137() doi 10.7554/eLife.37754 Abstract Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) represent two ends of a disease spectrum with shared clinical, genetic and pathological features. These...

PLoS biology 2018 07 1616(7) e2005840 doi 10.1371/journal.pbio.2005840 Abstract Clustered, regularly interspaced, short palindromic repeat (CRISPR)-CRISPR-associated 9 (Cas9) genome editing is revolutionizing fundamental...

Cell reports 24(3) 630-641 pii 10.1016/j.celrep.2018.06.066 Abstract The immunosuppressive transmembrane protein PD-L1 was shown to traffic via the multivesicular body (MVB) and to be released on exosomes. A high-content siRNA...

Cell 174(2) 497 pii 10.1016/j.cell.2018.06.051 Abstract

Nature communications 2018 07 139(1) 2724 doi 10.1038/s41467-018-05072-0 Abstract Identifying tumor antigen-specific T cells from cancer patients has important implications for immunotherapy diagnostics and therapeutics. Here,...

Genome biology 2018 07 1219(1) 88 doi 10.1186/s13059-018-1464-7 Abstract BACKGROUND DNA methylation is a heritable epigenetic mark, enabling stable but reversible gene repression. In mammalian cells, DNA methyltransferases...

Molecular cell 2018 06 2871(1) 56-72.e4 pii 10.1016/j.molcel.2018.06.003 Abstract Chromatin remodeling complexes play essential roles in metazoan development through widespread control of gene expression, but the precise...

American journal of public health 2015 04 23105(6) 1120-7 doi 10.2105/AJPH.2014.302313 Abstract OBJECTIVES We estimated the prevalence of any drinking and binge drinking from 2002 to 2012 and heavy drinking from 2005 to 2012 in...

Evidence-based complementary and alternative medicine : eCAM 2018 06 072018() 9521086 doi 10.1155/2018/9521086 Abstract Showering is the most common form of bathing worldwide. Whole-body immersion bathing in warm water (~40°C)...

Cell 173(2) 278-280 doi 10.1016/j.cell.2018.03.047 Abstract

Obesity (Silver Spring, Md.) 2011 06 1620(2) 421-7 doi 10.1038/oby.2011.171 Abstract The objective of this study was to examine whether lifestyle factors were associated with 5-year change in abdominal fat measured by computed...