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Critical Care General

Vascular access for renal replacement therapy among 459 critically ill patients: a pragmatic analysis of the randomized AKIKI trial.

Apr 12, 2021

Vascular access for renal replacement therapy (RRT) is routine question in the intensive care unit. Randomized trials comparing jugular and femoral sites have shown similar rate of nosocomial events a...

Mild Primary Hyperparathyroidism Linked With Adverse Cardiovascular Events

Apr 08, 2021

“The relationship between mild primary hyperparathyroidism (pHPT) and cardiovascular (CV) disease has not been fully understood,” explains Stella Bernardi, MD, PhD. “Previous research has shown ...

Transient global amnesia: Signal alteration in 2D/3D T2-FLAIR sequences.

Apr 08, 2021

Transient global amnesia (TGA) is one of the most enigmatic syndromes in clinical neurology. The detection rate of TGA lesions in 2D/3D FLAIR sequences has not been evaluated.A total of 201 patients (...

Heparin binding protein in severe COVID-19-A prospective observational cohort study.

Apr 08, 2021

Neutrophil-derived heparin binding protein (HBP; also known as azurocidin or CAP-37) is a key player in bacterial sepsis and a promising biomarker in severe infections. The aims of this study were to ...

Regulated hypothermia in response to endotoxin in birds.

Apr 08, 2021

The costs associated with immune and thermal responses may exceed its benefits to the host during severe inflammation. In this case, regulated hypothermia instead of fever can occur in rodents as a be...

Treatment-dose LMWH versus prophylactic/intermediate dose heparins in high risk COVID-19 inpatients: Rationale and design of the HEP-COVID Trial.

Apr 08, 2021

Coronavirus disease-2019 (COVID-19) has been associated with significant risk of venous thromboembolism (VTE), arterial thromboembolism (ATE), and mortality particularly among hospitalized patients wi...

The role of pirfenidone in the treatment of interstitial pneumonia with autoimmune features.

Apr 08, 2021

No approved pharmacotherapies are available for patients with interstitial pneumonia with autoimmune features (IPAF). In the present work, we aimed to evaluate the efficacy and safety of pirfenidone f...

Awake venoarterial extracorporeal membrane oxygenation for refractory cardiogenic shock.

Apr 08, 2021

Venoarterial-extracorporeal membrane oxygenation (VA-ECMO) is currently one of the first-line therapies for refractory cardiogenic shock (CS), but its applicability is undermined by the high morbidity...

Diagnostic imaging in acute interstitial pneumonia in foals: High variability of interpretation of chest radiographs and good conformity between ultrasonographic and post-mortem findings.

Apr 08, 2021

Acute interstitial pneumonia (AIP) in foals is a rare but challenging syndrome. Diagnostic imaging is crucial for its diagnosis. While there are some reports on radiographic findings, ultrasound is sp...

Does Racial Disparity Exist Among Inpatient Admissions for Heart Attacks in Wisconsin?

Apr 08, 2021

Acute myocardial infarction (AMI), or heart attack, carries a high inpatient death risk. Few national studies suggest race affects the outcomes of inpatients with AMI. In Wisconsin, an assessment of r...

In vitro comparison of harvesting site effects on cardiac extracellular matrix hydrogels.

Apr 08, 2021

Cardiac extracellular matrix (cECM) derived hydrogel has been investigated to treat myocardial infarction through animal studies and clinical trials. The tissue harvesting site commonly selects porcin...

CT appearances of pleural infection: analysis of the Second Multi-centre Intra-pleural Sepsis Trial (MIST 2) cohort.

Apr 08, 2021

To determine the prevalence of pleural abnormalities and describe the computed tomography (CT) features observed in a well-characterised population of patients with pleural infection.A retrospective s...

Investigation and assessment of neutrophil dysfunction early after severe burn injury.

Apr 08, 2021

Extensive burn injury results in a complex immune response that is associated with mortality and prognosis. Studies on acquired immune and the development of sepsis in burn patients have been reported...

The RD2 pathogenicity island modifies the disease potential of the group A .

Apr 08, 2021

Serotype M28 isolates of the group A (GAS; ) are non-randomly associated with cases of puerperal sepsis, a potentially life-threatening infection that can occur in women following childbirth. Previou...

Predicting caregiver burden over the first 4 months after acute traumatic brain injury in Latin America: a multi-country study.

Apr 08, 2021

: Traumatic brain injury (TBI) rates and outcomes are worse in Latin American countries relative to high-income countries. This study examined whether cognitive dysfunction, depressive mood, and poor ...

Early Stage Longitudinal Subcortical Volumetric Changes following Mild Traumatic Brain Injury.

Apr 08, 2021

: To investigate early brain volumetric changes from acute to 6 months following mild traumatic brain injury (mTBI) in deep gray matter regions and their association with patient 6-month outcome.: Fi...

LITAF acts as a novel regulator for pathological cardiac hypertrophy.

Apr 08, 2021

Pathological hypertrophy generally progresses to heart failure. Exploring effective and promising therapeutic targets might lead to progress in preventing its detrimental outcomes. Our current knowled...

Weight change and the incidence of heart failure in the Korean population: data from the National Health Insurance Health checkup 2005-2015.

Apr 08, 2021

Heart failure (HF) is associated with obesity, but the relationship between weight change and HF is inconsistent. We examined the relationship between weight change and the incidence of HF in the Kore...

Emerging mechanisms and targeted therapy of ferroptosis in cancer.

Apr 05, 2021

Ferroptosis is an iron- and lipid ROS-dependent form of programmed cell death that is distinct from other forms of regulatory cell death at the morphological, biological and genetic levels. Emerging e...

Interleukin-6 in Amniotic Fluid: A Reliable Marker for Adverse Outcomes in Women in Preterm Labor and Intact Membranes.

Apr 05, 2021

Amniotic fluid (AF) interleukin-6 (IL-6) concentration has been associated to preterm delivery and perinatal morbidity and mortality in women with preterm labor and intact membranes. Nevertheless, the...

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