Apr 22, 2021

Human induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs) have been used extensively to model inherited heart diseases, but hiPSC-CM models of ischemic heart disease are lacking. Here our...

Apr 19, 2021

In the United States, non-obstructive coronary disease has been on the rise, and each year, nearly one million adults suffer myocardial infarction, 70% of which are non-ST-segment elevation myocardial...

Apr 19, 2021

Up to 14% of patients undergoing carotid endarterectomy (CEA) with continuous electroencephalographic (EEG) neuromonitoring require shunt placement due to EEG changes. Initial studies of transcarotid ...

Apr 19, 2021

Non-emergency percutaneous coronary intervention (PCI) has lower risk of stroke than emergency PCI. With increasing elective PCI and increasing risk of stroke after PCI, risk factors for stroke or tra...

Apr 19, 2021

Few small studies have described hospital-acquired infections (HAIs) during COVID-19.What patient characteristics in critically ill patients with COVID-19 are associated with HAIs and how do HAIs asso...

Apr 15, 2021

Randomized controlled trials have demonstrated the importance of time to endovascular therapy (EVT) in clinical outcomes in large vessel occlusion (LVO) acute ischemic stroke. Delays to treatment are ...

Apr 15, 2021

Thrombotic diseases like ischemic stroke are common complications of essential thrombocythemia (ET) due to abnormal megakaryopoiesis and platelet dysfunction. Ischemic stroke in ET can occur as a resu...

Apr 15, 2021

Endovascular treatment of large vessel occlusion in acute ischemic stroke patients is difficult to establish in remote areas, and time dependency of treatment effect increases the urge to develop heal...

Apr 15, 2021

This study was performed to investigate the relationship between the aspartate transaminase and/or alanine transaminase ratio (DRR) and long-term mortality of patients diagnosed with sepsis or septic ...

Apr 15, 2021

We sought to investigate the risk of pediatric surgical mortality associated with the combined effects of key preoperative comorbidities and race.We performed a retrospective study that included infan...

Apr 15, 2021

To report available information in the literature regarding frequency, indications, types of antibiotic usage, duration, and their efficacy in Covid-19 infected patients.The search was conducted on Ap...

Apr 15, 2021

Bronchoscopy is widely used and regarded as standard of care in most intensive care units (ICUs). Data concerning recommendations for on-call bronchoscopy are lacking.Evaluation of recommendations, co...

Apr 15, 2021

Elevated troponin levels are found in a significant number of patients who are diagnosed with acute embolic stroke (AES) after first diagnosed atrial fibrillation (AF). These myocardial injuries, whic...

Apr 15, 2021

previous studies evaluating external stents for saphenous vein grafts (SVG) in CABG were limited to on-pump isolated CABG and single grafting technique with one external stent per patient. The objecti...

Apr 15, 2021

An acute ST-elevation myocardial infarction (STEMI) is a very serious type of heart attack and a profoundly life-threatening medical emergency, and percutaneous coronary intervention (PCI) is the pref...

Apr 15, 2021

Sepsis is a major public health concern, with high mortality and morbidity, especially among trauma patients. It is characterized by a systemic inflammatory response syndrome (SIRS) occurring in respo...

Apr 15, 2021

In some cases, autopsy is the first opportunity to find a previously unrecognized critical infection. Pathogens are identified by various methods, such as microscopic examination, special stains, cult...

Apr 15, 2021

Macrophages undergo profound metabolic reprogramming to join key immunoregulatory functions, which can be initiated by pattern recognition receptors. TREM2, a macrophage phagocytic receptor, plays piv...

Apr 15, 2021

Current evidence regarding the protective effect of mouthguard use on symptom severity in children and adolescents who sustain sport-related concussions is insufficient to make clinical recommendation...

Apr 15, 2021

We sought to determine the secondary overtriage rate of pediatric trauma patients admitted to pediatric trauma centers. We hypothesized that pediatric secondary overtriage (POT) would constitute a lar...