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Critical Care General

Continuous positive airway pressure improves work of breathing in pediatric chronic heart failure.

May 17, 2021

Sleep disordered breathing (SDB) is common in adults with chronic heart failure (CHF), but its prevalence in children remains unclear. Continuous positive airway pressure (CPAP) is the treatment of SD...

Ultrasonic blood flowmeter with a novel Xero algorithm for a mechanical circulatory support system.

May 17, 2021

Mechanical circulatory support systems (MCSSs) are crucial devices for transplants in patients with heart failure. The blood flowing through the MCSS can be recirculated or even stagnated in the event...

Simplified frontal EEG in adults under veno-arterial extracorporeal membrane oxygenation.

May 17, 2021

EEG-based prognostication studies in intensive care units often rely on a standard 21-electrode montage (EEG) requiring substantial human, technical, and financial resources. We here evaluate whether ...

Intestinal amyloidosis: Clinical manifestations and diagnostic challenge.

May 13, 2021

Amyloidosis is a heterogeneous group of diseases in which the extracellular deposition of abnormal fibrillar proteins disrupts tissue structure and function. Intestinal involvement is a very rare mani...

Hsa Circ 001839 Promoted Inflammation in Renal Ischemia-Reperfusion Injury Through NLRP3 by miR-432-3p.

May 13, 2021

In recent years, increasing discovery of the extremely important regulatory effects of circular RNAs on biological development, angiogenesis, tumor genesis, and development, as well as stem cell proli...

Mortality and Morbidity of Infants Born Extremely Preterm at Tertiary Medical Centers in China From 2010 to 2019.

May 13, 2021

Extreme prematurity is associated with a substantial burden on health care systems worldwide. However, little is known about the prognosis of infants born extremely preterm in developing countries, su...

The Golden Hour: Sustainability and Clinical Outcomes of Adequate Time to Antibiotic Administration in Children with Cancer and Febrile Neutropenia in Northwestern Mexico.

May 13, 2021

Time to antibiotic administration (TTA) is a commonly used standard of care in pediatric cancer settings in high-income countries. Effective interventions to improve outcomes in cancer patients with f...

The effect of early vasopressin use on patients with septic shock: A systematic review and meta-analysis.

May 13, 2021

The effect of early vasopressin initiation on clinical outcomes in patients with septic shock is uncertain. A systematic review and meta-analysis was performed to evaluate the impact of early start of...

Inhaled bacteriophage therapy in a porcine model of pneumonia caused by Pseudomonas aeruginosa during mechanical ventilation.

May 13, 2021

Pseudomonas aeruginosa is a main cause of ventilator-associated pneumonia (VAP) with drug-resistant bacteria. Bacteriophage therapy has experienced resurgence to compensate for the limited development...

Genetic and non-genetic factors associated with health and vitality traits in beef calves.

May 13, 2021

Awareness and interest in calf health and wellbeing is intensifying, prompting change in the management and breeding decisions of producers and associated policy-makers. The objectives of the present ...

Nasopharyngeal Pneumococcal Colonization Density is Associated with Severe Pneumonia in Young Children in the Lao PDR.

May 13, 2021

No studies have explored the association between pneumococcal nasopharyngeal density and severe pneumonia using the WHO 2013 definition. In Lao People's Democratic Republic (Lao PDR), we determine the...

Coronary plaque composition influences biomechanical stress and predicts plaque rupture in a morpho-mechanic OCT analysis.

May 13, 2021

Plaque rupture occurs if stress within coronary lesions exceeds the protection exerted by the fibrous cap overlying the necrotic lipid core. However, very little is known about the biomechanical stres...

Macrophage-preferable delivery of the leucine-rich repeat domain of NLRX1 ameliorates lethal sepsis by regulating NF-κB and inflammasome signaling activation.

May 13, 2021

Sepsis is an acute systemic inflammatory disease triggered by bacterial infection leading organ dysfunctions that macrophages are responsible for major triggering of systemic inflammation. Treatment o...

Amikacin Combined with Fosfomycin for Treatment of Neonatal Sepsis in the Setting of Highly Prevalent Antimicrobial Resistance.

May 13, 2021

Antimicrobial resistance (particularly by extended spectrum β-lactamase and aminoglycoside modifying enzyme production) in neonatal sepsis is a global problem, particularly in low- and middle-income ...

Infantile orbital abscess: clinical presentation, microbiological profile, and management outcomes.

May 13, 2021

: Orbital abscesses in children are not uncommon. Unless managed in a timely fashion, they can potentially lead to vision-threatening as well as life-threatening complications. The objective of this s...

The utility of decompressive craniectomy in severe traumatic brain injury in Saudi Arabia trauma centers.

May 13, 2021

: Decompressive craniectomy (DC) represents an effective method for intracranial pressure (ICP) reduction in cases of severe traumatic brain injury (TBI). However, little is known regarding the attitu...

Noise Outcomes in Servicemembers Epidemiology (NOISE) Study: Design, Methods, and Baseline Results.

May 13, 2021

Military Service members and Veterans commonly report hearing loss and tinnitus, both of which can result in significant disability. During military service, Service members are exposed to many differ...

Age-Related Vestibular and Ocular Motor Outcomes Following a Sport-Related Concussion.

May 13, 2021

Vestibular and ocular motor assessment is an emerging clinical assessment for sport-related concussion (SRC). The increased use of these assessments by clinicians calls for examination of outcomes in ...

Patient-Reported Outcomes in Cardiovascular Trials.

May 13, 2021

Patient-reported outcomes (PROs) are reports of a person's health status that provide a global perspective of patient well-being. PROs can be classified into four primary domains: global, mental, phys...

Mis-reporting of energy intake among older Australian adults: Prevalence, characteristics, and associations with quality of life.

May 13, 2021

Mis-reporting is common in dietary assessment, leading to misinterpretation of disease risk and could be important in older adults with increased chronic disease risk. This study investigated the prev...

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