Nov 01, 2021

Methicillin-resistant Staphylococcus aureus (MRSA) has become the most important pathogen of hospital-acquired (HA) or community-acquired (CA) infections. However, it is unclear of the cytokines respo...

Nov 01, 2021

Our national protocol for traumatic brain injury dictates that hypocoagulated patients with mild trauma and initial tomography scan with no intracranial traumatic changes must be hospitalized for 24 ...

Nov 01, 2021

Mesenchymal stromal cells (MSCs) are widely used in preclinical models of traumatic brain injury (TBI). Results are promising in terms of neurological improvement but are hampered by wide variability ...

Nov 01, 2021

Mechanical circulatory support (MCS) with an implantable left ventricular assist device (LVAD) is an established therapeutic option for advanced heart failure. Most of the currently used LVADs generat...

Oct 25, 2021

Mycoplasma hyopneumoniae is a major pathogen affecting pig herds and vaccination is the most utilized approach, despite providing partial protection. Age at vaccination, the delivery route, and vaccin...

Oct 25, 2021

Obesity is an independent risk factor for worse outcomes in various surgical settings. Whether obesity is a prognostic factor for postoperative morbidity and mortality of colorectal cancer (CRC) is in...

Oct 25, 2021

Sepsis and bloodstream infection are associated with significant morbidity and mortality, and early effective antimicrobial therapy has been demonstrated to improve patient outcomes. Traditional cultu...

Oct 25, 2021

Extracellular vesicles (EVs), including exosomes and microvesicles, are lipid bilayer particles naturally released from the cell. While exosomes are formed as intraluminal vesicles (ILVs) of the multi...

Oct 25, 2021

Current guidelines recommend empiric antifungal therapy in sepsis patients with high risk of invasive Candida infection. However, many different risk factors have been derived from multiple studies. T...

Oct 22, 2021

New research was presented at CHEST 2021, the virtual Annual International Scientific Assembly of the American College of Chest Physicians, from October 17-20. The features below highlight some of the...

Oct 18, 2021

The enteroinsular axis (EIA) is an energy regulatory system that modulates insulin secretion through the release of enteroendocrine factors (incretins). Despite the importance of energy homeostasis in...

Oct 18, 2021

 To estimate the effectiveness and efficiency of chest CT in children based on the suspected diagnosis in relation to the number of positive, negative, and inconclusive CT results. In this monocen...

Oct 18, 2021

Myocardial infarction (MI), one of the most severe types of heart attack, exerts a strong negative effect on heart muscle by causing a massive and rapid loss of cardiomyocytes. However, the existing t...

Oct 18, 2021

Arteriovenous malformations of the lower extremities (AVM) can present as simple or complex combined or syndromic forms (e.g. Parkes Weber Syndrome). We aimed to characterize the differences in clinic...

Oct 18, 2021

Decompressive craniectomy (DC) is highly effective in relieving intracranial hypertension, however patient selection, intracranial pressure threshold, timing, and long-term functional outcomes, are al...

Oct 18, 2021

Allogeneic hematopoietic cell transplantation (allo-HCT) can be curative for relapsed or refractory B-cell lymphomas (BCL), though outcomes are worse in aggressive disease and most patients will still...

Oct 14, 2021

More than 30 million adults in the United States are affected by CKD, but studies during the past 10-15 years indicate that CKD awareness is suboptimal. “Patient awareness of CKD is a critical first...

Oct 11, 2021

“Patients with mild COPD frequently present with chronic dyspnea and poor exercise capacity, often to a greater extent than would be expected based on their resting lung function values,” explains...

Oct 11, 2021

Sepsis is one of the leading causes of morbidity and mortality in the pediatric population worldwide. This study aimed to establish a correlation between platelet count and outcomes of severe sepsis/s...

Oct 11, 2021

Spotted gar (Lepisosteus oculatus) is a primitive ray-finned fish which has not undergone the third round whole genome duplication and commonly used as a model to study the evolution of immune genes. ...