Apr 06, 2020

Autosomal dominant hyper IgE syndrome (AD-HIES) caused by STAT3 gene mutation is a rare primary immunodeficiency disease. To better understand the disease, we described the clinical characteristics of...

Apr 06, 2020

Avian influenza A(H5N6) keeps evolving, causing outbreaks in birds and sporadic infections in human. Here we report a fatal pediatric infection caused by a novel reassortant H5N6 virus. The patient wa...

Apr 06, 2020

Non-alcoholic fatty liver disease (NAFLD) and human immunodeficiency virus (HIV) are independently associated with cardiovascular disease (CVD). However, the factors associated with NAFLD in persons l...

Apr 06, 2020

In ENSURE-AF (NCT02072434), the oral Factor Xa inhibitor edoxaban showed similar efficacy and safety vs enoxaparin-warfarin in patients undergoing electrical cardioversion of nonvalvular atrial fibril...

Apr 06, 2020

Prasugrel was approved at a lower dose in 2014 in Japan than in the West because East Asian patients are considered more susceptible to bleeding than Western patients. However, real-world outcomes wit...

Apr 06, 2020

Occlusive atherosclerotic disease of the anterior cerebral circulation is one of the most common causes of anterior circulation ischemia and stroke. Treatment options include medical therapies (includ...

Apr 06, 2020

The early recognition of invasive bacterial infections (IBI) in children can be difficult. Clinically it is often challenging to differentiate between the early stages of an IBI and a benign self-limi...

Apr 06, 2020

Ceftobiprole is a new therapeutic option for bacterial pneumonia, with activity against most antimicrobial resistant gram-positive cocci, including methicillin-resistant Staphylococcus aureus. Data on...

Apr 06, 2020

The decision to perform a total knee arthroplasty (TKA) on a previously infected knee is made complicated by the higher risk for both a periprosthetic joint infection (PJI) and early failure. There is...

Apr 06, 2020

We review a series of isolated septic facet joints (ISFJ) that present as a distinct clinical entity compared with spondylodiscitis. We aim to raise awareness that septic facet joints are not a rare e...

Apr 06, 2020

To study the epidemiology of hospitalized serious infections in people with gout.We identified people with gout hospitalized with a primary diagnosis of pneumonia, sepsis/bacteremia, urinary tract inf...

Apr 06, 2020

Determine the frequency of polytraumatized pediatric patients involved in motorcycle accidents treated at the Pediatric Hospital of Sinaloa between 2015 and 2017, as well as to determine the frequency...

Apr 06, 2020

Dipeptidyl peptidase-4 inhibitors (or gliptins), a class of antidiabetic drugs, have recently been shown to have protective actions in the central nervous system. Their cellular and molecular mechanis...

Apr 06, 2020

Management of panfacial fractures is critical and often difficult in adults; however, there is little to no literature regarding these fractures in the pediatric population. In this study, we present ...

Apr 06, 2020

Decreases in energy metabolism following traumatic brain injury (TBI) are attributed to impairment of glycolytic flux and oxidative phosphorylation. Glucose utilization post-TBI is decreased while adm...

Apr 06, 2020

To explore the potential utility of head acceleration event (HAE) measurements to augment identification of players for further concussion screening in non-helmeted contact sport.Prospective observati...

Apr 06, 2020

Initial screening for proteinuria by urine dipstick test (UDT) may be useful for predicting clinical outcomes. The Shinken Database includes all the new patients visiting the Cardiovascular Institute ...

Apr 06, 2020

Various postoperative predictive markers following cardiovascular surgery have been examined for use in the current aging population. The controlling nutritional status (CONUT) score, which is advocat...

Apr 06, 2020

Admission to high-acuity intensive care units (ICUs) has been associated with improved outcomes compared to low-acuity ICUs, although the mechanism for these findings is unclear.Do high-acuity ICUs mo...

Apr 06, 2020

The presence of carotid artery disease is known risk factor for perioperative stroke in cardiac surgery. The optimal management of patients with concomitant heart and carotid artery disease is not kno...