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Critical Care General

nAnnexin A1 is a Potential Novel Biomarker of Congestion in Acute Heart Failure.

Jun 01, 2020

The study sought to identify the role of Annexin A1 as a congestion marker in acute heart failure, and to identify its putative role in predicting clinical outcomes.Annexin A1 (AnxA1) is a protein tha...

Wearable Patch Based Estimation of Oxygen Uptake and Assessment of Clinical Status during Cardiopulmonary Exercise Testing in Patients with Heart Failure.

Jun 01, 2020

To estimate oxygen uptake (VO) from cardiopulmonary exercise testing (CPX) using simultaneously recorded seismocardiogram (SCG) and electrocardiogram (ECG) signals captured with a small wearable patch...

Aortic Insufficiency during HeartMate 3 Left Ventricular Assist Device Support: AI in HeartMate 3.

Jun 01, 2020

Aortic insufficiency (AI) is associated with morbidity and mortality in patients with continuous-flow left ventricular assist devices (LVADs), whereas its impact on the HeartMate 3 LVAD cohorts remain...

A single center retrospective cohort study evaluating use of direct oral anticoagulants (DOACs) in morbidly obese veteran population.

Jun 01, 2020

Direct oral anticoagulants (DOACs) are preferred over warfarin for the treatment of venous thromboembolism (VTE) as well as atrial fibrillation (AF). The efficacy and safety of fixed dose regimen of D...

Fenestrated Repair Improves Perioperative Outcomes but Lacks a Hospital Volume Association for Complex Abdominal Aortic Aneurysms.

Jun 01, 2020

Complex abdominal aortic aneurysms (cAAAs) have traditionally been treated with an open surgical repair (OSR). Over the past decade, fenestrated endovascular graft repair (FEVAR) has emerged as a viab...

Follow-Up Care & Post-Stroke Readmission

May 28, 2020

Research indicates that more than 750,000 patients per year are hospitalized for stroke in the US, with 50% experiencing lasting effects. Among stroke survivors, 5% to 14% experience another stroke in...

Subcapsular Renal Hematoma in Simultaneous Pancreas Kidney Transplantation.

May 28, 2020

Subcapsular renal hematoma (SRH) is a challenging condition, which may jeopardize kidney function or constitute a life-threatening event. This is particularly true in single-kidney patients, such as k...

Transperineal free-hand mpMRI fusion targeted biopsies under local anesthesia for Prostate Cancer Diagnosis: a multicenter prospective study of 1,014 cases.

May 28, 2020

No large multicentre prospective studies ever addressed the outcomes of mpMRI targeted fusion transperineal biopsy (TPFBx) under local anesthesia (LA). The debate upon best biopsy modality is still op...

Potential therapeutic effect of Qingwen Baidu Decoction against Corona Virus Disease 2019: a mini review.

May 28, 2020

The Corona Virus Disease 2019 (COVID-19) is an acute respiratory infectious disease. At present, COVID-19 has no specific therapeutic drugs, and the main clinical treatment is symptomatic treatment an...

Acute Esophageal Necrosis in a Septic Patient with a History of Cardiovascular Disease.

May 28, 2020

Acute esophageal necrosis (AEN), or colloquially named "black esophagus," is a rare clinical condition often associated with ischemic injury to the esophagus secondary to splanchnic vasoconstriction d...

Subcutaneous Selatogrel Inhibits Platelet Aggregation in Patients With Acute Myocardial Infarction.

May 28, 2020

Oral P2Y receptor antagonists exhibit delayed onset of platelet inhibition in patients with acute myocardial infarction (AMI). Selatogrel is a potent, highly selective, and reversible P2Y receptor ant...

Apixaban versus No Anticoagulation in Patients Undergoing Long-Term Dialysis with Incident Atrial Fibrillation.

May 28, 2020

The relative efficacy and safety of apixaban compared with no anticoagulation have not been studied in patients on maintenance dialysis with atrial fibrillation. We aimed to determine whether apixaban...

OUTCOMES AND STRATEGY OF TAILORED ANTIPLATELET THERAPY WITH TICAGRELOR IN PATIENTS UNDERGOING TRANSCAROTID ARTERY REVASCULARIZATION (TCAR).

May 28, 2020

Antiplatelet drug resistance is associated with periprocedural ischemic complications in patients undergoing intravascular stent implantation. Nonresponders are subject to increased risk of stent thro...

When Zoonotic Organisms Cross Over-Trueperella pyogenes Endocarditis Presenting as a Septic Embolic Stroke.

May 28, 2020

Infective endocarditis (IE) remains a significant cause of morbidity and mortality worldwide, with numerous pathogens as culprits. We present a case of IE that evolved to a septic embolic stroke cause...

Complex Wound Closure Following Mysterious and Vicious Animal Attack.

May 28, 2020

Animal attacks are a worrisome and dangerous entity that occur at high volumes and are evaluated frequently by ER physicians, primary care physicians, trauma teams, acute care surgeons, and plastic su...

Diagnostic Value of miR-103 in Patients with Sepsis and Noninfectious SIRS and Its Regulatory Role in LPS-Induced Inflammatory Response by Targeting TLR4.

May 28, 2020

Sepsis is a life-threatening condition and a systemic inflammatory response syndrome (SIRS) driven by infection. This study aimed at investigating the expression of microRNA-103 (miR-103) in sepsis pa...

Relationship Satisfaction and Depression after Traumatic Brain Injury: An Actor-Partner Interdependence Model of Patients and Caregivers in Mexico and Colombia.

May 28, 2020

Traumatic brain injury (TBI) represents a major public health concern, particularly in low- and middle-income countries like in Latin America. Family members are often caregivers for individuals with ...

Human adipose-derived mesenchymal stem cells for acute and sub-acute TBI.

May 28, 2020

In the U.S., approximately 1.7 million people suffer traumatic brain injury each year, with many enduring long-term consequences and significant medical and rehabilitation costs. The primary injury ca...

The Attenuation of Traumatic Brain Injury via Inhibition of Oxidative Stress and Apoptosis by Tanshinone IIA.

May 28, 2020

Traumatic brain injury (TBI) is a major source of mortality and long-term disability worldwide. The mechanisms associated with TBI development are poorly understood, and little progress has been made ...

Safety and Feasibility of Performing Fenestrated Endovascular Abdominal Aneurysm Repair Using a Portable C-arm Without Fusion Technology: A Single-Center Experience.

May 28, 2020

Objective Most centers performing fenestrated endovascular aneurysm repair (F-EVAR) use hybrid rooms with fusion technology for mapping. We present our experience of successfully performing F-EVAR usi...

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