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Critical Care General

Brain Imaging Signs and Health-Related Quality of Life after Acute Ischemic Stroke: Analysis of ENCHANTED Alteplase Dose Arm.

Jul 27, 2020

The influence of specific brain lesions on health-related quality of life (HRQoL) after acute ischemic stroke (AIS) is uncertain. We aimed to identify imaging predictors of poor HRQoL in alteplase-tre...

Less invasive treatment for broad ligament hernia: A case report.

Jul 23, 2020

Among diseases that cause small bowel obstruction, internal hernia may result in severe outcomes. Therefore, emergency laparotomy has been often performed, but it may be invasive. We experienced a cas...

RNA-seq analysis of the key long noncoding RNAs and mRNAs related to cognitive impairment after cardiac arrest and cardiopulmonary resuscitation.

Jul 23, 2020

Cardiac arrest (CA) is the leading cause of death around the world. Survivors after CA and cardiopulmonary resuscitation (CPR) develop moderate to severe cognitive impairment up to 60% at 3 months. Ac...

The effect of interleukin 6 deficiency on myocardial signal transduction pathways activation induced by bacterial lipopolysaccharide in young and old mice.

Jul 23, 2020

Exaggerated release of proinflammatory mediators during sepsis contributes to inadequate vasodilatation and depressed myocardial contractility, which lead to development of shock and circulatory colla...

Is Lumbar Puncture Avoidable in Low-Risk Neonates with Suspected Sepsis?

Jul 23, 2020

 Performing lumbar punctures (LP) in all clinically suspected neonatal sepsis, as per current recommendations, results in many "negative" LPs. LPs are not without their own risks. With the intention...

Cancer and Pregnancy: National Trends.

Jul 23, 2020

 Cancer and pregnancy are likely increasing; however, updated estimates are needed to optimally address the unique needs of this patient population. The study aims to estimate the prevalence of canc...

Radiological Findings of COVID-19 in Children: A Systematic Review and Meta-Analysis.

Jul 23, 2020

The majority of the children with SARS-CoV-2 infection present with respiratory symptoms, hence various chest imaging modalities have been used in the management. Knowledge about the radiological find...

Coumaric acid analogues inhibit growth and melanin biosynthesis in Cryptococcus neoformans and potentialize amphotericin B antifungal activity.

Jul 23, 2020

Fungal infections are on the rise, since the imunocompromised population is increasing due to AIDS/HIV, organ transplant and chemotherapy. Many environmental and pathogenic fungi are able to accomplis...

Effect of depression on health behavior among myocardial infarction survivors in the United States.

Jul 23, 2020

The purpose of this study was to evaluate the effect of depression on health behavior among myocardial infarction (MI) survivors.This retrospective, cross-sectional study used publicly available 2015 ...

Best-Worst Scaling Study to Identify Complications Patients Want to Be Informed About Prior to Abdominal Aortic Aneurysm Surgery.

Jul 23, 2020

Surgeons must discuss the most severe surgical complications with their patients while making a treatment decision. However, it is unclear which complications patients deem most severe. This study aim...

Prognostic significance of pre-procedural prognostic nutritional index in patients with carotid artery stenting.

Jul 23, 2020

Inflammation and malnutrition play a critical role in the outcomes of patients undergoing carotid artery stenting (CAS). Prognostic nutritional index (PNI) is commonly utilized to evaluate the peri-op...

Serum level of soluble CD14 subtype predicts long-term prognosis in sepsis patients with cardiac dysfunction.

Jul 23, 2020

Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection, and some sepsis patients will develop cardiac dysfunction. Sepsis-induced cardiac dysfunc...

The protective effect of vitexinin septic encephalopathy by reducing leukocyte-endothelial adhesion and inflammatory response.

Jul 23, 2020

Despite advances in therapeutic strategies and critical care management, septic encephalopathy (SE) is still a leading cause of infection-associated death in intensive care units (ICUs). Vitexin, a fl...

Septic cavernous sinus thrombosis-Case series and review of the literature.

Jul 23, 2020

Septic cavernous sinus thrombosis (CST) is a rare, life-threatening disease with infectious thrombosis causing associated complications resulting in high morbidity and mortality. We report a series of...

Association Between Concussion History and Factors Relating to Cognitive, Behavioral, and Emotional Health Among American High School Athletes: A Cross-sectional Analysis.

Jul 23, 2020

The cognitive, behavioral, and emotional deficits that may be associated with sports-related concussions among adolescents are unclear.We examined the association between reported concussion history a...

The closed-head impact model of engineered rotational acceleration (CHIMERA) as an application for traumatic brain injury pre-clinical research: A status report.

Jul 23, 2020

Closed-head traumatic brain injury (TBI) is a worldwide concern with increasing prevalence and cost to society. Rotational acceleration is a primary mechanism in TBI that results from tissue strains t...

Pre-injury health status and excess mortality in persons with traumatic brain injury: A decade-long historical cohort study.

Jul 23, 2020

An increasing number of patients are able to survive traumatic brain injuries (TBIs) with advanced resuscitation. However, the role of their pre-injury health status in mortality in the following year...

Porcine versus Bovine Bioprosthetic Aortic Valves: Long-term Clinical Results.

Jul 23, 2020

Previous studies have reported superior hemodynamic performance with bovine bioprosthetic aortic valves compared with porcine valves. However, conflicting results mean the long-term effect on survival...

Cerebral hemorrhage in the LVAD patient: A case series and literature review.

Jul 23, 2020

A left ventricular assist device (LVAD) is used in certain heart failure cases, but LVADs can have significant neurological complications including intracranial hemorrhages (ICH). Prediction and manag...

Evidence-based practices for acute respiratory failure and acute respiratory distress syndrome: A systematic review of reviews.

Jul 23, 2020

The recent pandemic highlights the essential nature of optimizing the use of invasive mechanical ventilation (IMV) in complex critical care settings. This review of reviews maps evidence-based practic...

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