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Critical Care General

A pregnancy-specific reference interval for procalcitonin.

Dec 14, 2020

Sepsis is a leading cause of maternal death, and developing diagnostic tests for infection is increasingly important to reduce maternal mortality. The existing inflammatory markers, like C-reactive pr...

Clinical prioritisation of revision knee surgical procedures: BASK working group consensus document.

Dec 14, 2020

Elective orthopaedic surgery during the Covid-19 pandemic requires careful case prioritisation. We aimed to produce consensus-based guidelines on the prioritisation of revision total knee arthroplasty...

Serum Substance P Concentration in Children with Traumatic Brain Injury: A First Report.

Dec 14, 2020

To review the clinic value and severity assessment of serum substance P (SP) concentration in children with different degrees of traumatic brain injury (TBI) through analyzing correlations with outcom...

Prognostic analysis of emergency decompressive craniectomy for severe traumatic brain injury patients with bilateral fixed dilated pupils.

Dec 14, 2020

For severe traumatic brain injury (sTBI) patients with bilateral fixed dilated pupils (BFDP), the value of aggressively decompressive craniectomy (DC) treatment is still controversial. The objective o...

Measuring the Optic Nerve Sheath Diameter with Ultrasound in Acute Middle Cerebral Artery Stroke Patients.

Dec 14, 2020

Measurement of the optic nerve sheath diameter (ONSD) with ultrasound enables non-invasive and indirect assessment of increased intracranial pressure (ICP). Although most of the studies were employed ...

Gut microbiome - A potential mediator of pathogenesis in heart failure and its comorbidities: State-of-the-art review.

Dec 14, 2020

Gut microbiome (GMB) has been increasingly recognized as a contributor to development and progression of heart failure (HF), immune-mediated subtypes of cardiomyopathy (myocarditis and anthracycline-i...

Age-dependent anticoagulant therapy for atrial fibrillation patients with intermediate risk of ischemic stroke: A nationwide population-based study.

Dec 14, 2020

Although older age is one of the most important risk factors for stroke in atrial fibrillation (AF), it is unclear whether an age threshold exists for which oral anticoagulants (OACs) are beneficial f...

Impact of the shift to a fibrinolysis-first strategy on care and outcomes of patients with ST-segment-elevation myocardial infarction during the COVID-19 pandemic-The experience from the largest cardiovascular-specific centre in China.

Dec 14, 2020

The impact of fibrinolysis-first strategy on outcomes of patients with ST-segment-elevation myocardial infarction (STEMI) during the COVID-19 pandemic was unknown.Data from STEMI patients presenting t...

Heart failure in people with type 2 diabetes vs. those without diabetes: A retrospective observational study from South India.

Dec 14, 2020

Despite diabetes being an independent risk for HF, only some DM patients develop HF and hence our aim was to compare the clinical features of DM with and without HF and non-DM with and without HF.A re...

Oleanolic Acid Improves the Symptom of Renal Ischemia Reperfusion Injury via the PI3K/AKT Pathway.

Dec 10, 2020

The aim of this study was to investigate the therapeutic effect of oleanolic acid (OA) on the renal ischemia reperfusion injury (RIRI) and the possible mechanism.The RIRI model was successfully establ...

Kawasaki Disease Shock Syndrome versus Septic Shock: Early Differentiating Features Despite Overlapping Clinical Profiles.

Dec 10, 2020

To compare the clinical features and resuscitative measures of children with Kawasaki disease shock syndrome versus septic shock.In this retrospective case-control study, children with KDSS admitted t...

Design and evaluation of ciprofloxacin loaded collagen chitosan oxygenating scaffold for skin tissue engineering.

Dec 10, 2020

Hypoxia and sepsis are the key concerns towards modern regenerative medicine. Oxygen generating biomaterials having antibacterial property aim to answer these concerns. Hypoxia and Sepsis promote reac...

Epidemiology and Outcomes of Acute Kidney Injury in COVID-19 Patients with Acute Respiratory Distress Syndrome: A Multicenter Retrospective Study.

Dec 10, 2020

Acute kidney injury (AKI) is associated with increased mortality in patients with acute respiratory distress syndrome (ARDS). However, the epidemiological features and outcomes of AKI among COVID-19 p...

Estradiol resolves pneumonia via ER-β regulatory T cells.

Dec 10, 2020

Current treatments for pneumonia (PNA) are focused on the pathogens. Mortality from PNA-induced acute lung injury (PNA-ALI) remains high, underscoring the need for additional therapeutic targets. Clin...

Clinicopathologic Features of Tissue Granulomas in Transplant Recipients: A Single Center Study in a Nontuberculosis Endemic Region.

Dec 10, 2020

There is a paucity of literature about tissue granulomas in transplant patients.To characterize the clinicopathologic features of granulomas in this population and develop a clinically judicious appro...

Trends in Cardiovascular Complications and Mortality among Patients with Diabetes in South Korea.

Dec 10, 2020

We investigated the cardiovascular complications and mortality rates of patients with diabetes in South Korea. The rates of hospitalization due to cardiovascular complications and mortality were analy...

Effect Of Pre-Operative Β-Blocker Therapy After Cabg Surgery: Long-Term Survival And Postoperative Complications.

Dec 10, 2020

Introduction Perioperative medication in cardiac surgery recommends β-blockers' use but it is not clear if its prescription should be started before or after cardiac surgery. Objectives To determine ...

Burden of carbapenem non-susceptible infections in high-risk patients: systematic literature review and meta-analysis.

Dec 10, 2020

Owing to their resistance to an important class of antibiotics, the prevention and treatment of carbapenem-resistant (CR)/non-susceptible Gram-negative (GN) infections has become an important public h...

Menstrual blood-derived stromal cells modulate functional properties of mouse and human macrophages.

Dec 10, 2020

Menstrual blood-derived stromal cells (MenSCs) are emerging as a strong candidate for cell-based therapies due to their immunomodulatory properties. However, their direct impact on innate immune popul...

Patient-specific cruciate-retaining total knee replacement with individualized implants and instruments (iTotal™ CR G2).

Dec 10, 2020

Treatment of tricompartimental osteoarthritis (OA) using customized instruments and implants for cruciate-retaining total knee arthroplasty. Use of patient-specific instruments and implants (ConforMIS...

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