Multi-Organ Immune-related Adverse Events from Immune Checkpoint Inhibitors
1. Co-occurrences could be clustered together into 7 clusters based on the predominant organ...
Read More
chronic-disease
Benralizumab associated with histologic response in eosinophilic esophagitis
1. In this randomized controlled trial, benralizumab, an anti-interleukin-5 receptor (anti-IL-5R)...
Read More
Tisotumab Vedotin as Second or Third-Line Therapy for Recurrent Cervical Cancer
1. Median overall survival was 11.5 months in the tisotumab vedotin group and 9.5 months in the...
Read More
Oral sebetralstat provides early symptom relief for hereditary angioedema attacks
1. In this randomized controlled trial, oral sebetralstat provided faster times to the beginning...
Read More
Web-based cognitive behavioural therapy may be effective for treatment of bulimia nervosa
1. Patients with bulimia nervosa randomized to receive web-based cognitive behavioural therapy...
Read More
Financial incentives may be a viable option to promote smoking cessation
1. Incentivizing smoking cessation with financial rewards increased the likelihood of cessation...
Read More
Poor cardiovascular health is a risk factor for female infertility
1. Cardiovascular health and infertility are negatively correlated with physical activity, BMI,...
Read More
Periodontitis in patients with diabetes and its association with diabetes-related complication
1. Periodontitis has a strong association with Type 2 Diabetes and is exacerbated by poor glycemic...
Read More
Immunotherapy-Based Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer
1. The complete response rates (pathological and clinical) were similar (~55%) in both groups. 2....
Read More
Poor sleep and elevation of liver function biomarkers may be predictive of liver cancer
1. Unhealthy sleep, as well elevations of liver enzymes and decreased levels of albumin and liver...
Read More
Metformin Linked to Lower Risk of Cardiometabolic Diseases, Cardiometabolic Mortality, and All-Cause Mortality in Cancer Survivors
1. Among US cancer survivors, metformin was associated with a lower risk of cardiometabolic...
Read More
Serum interleukins may be elevated in patients with obsessive-compulsive disorder
1. Serum interleukin-1β (IL-1β) and interleukin-6 (IL-6) levels were higher in...
Read More
Comparison of hip fracture risk assessment tools for elderly patients
1. Femoral neck bone mineral density (FNBMD) alone discriminated 5-year hip fracture risk at least...
Read More
Subcutaneous amivantamab with lazertinib is non-inferior to intravenous administration, with fewer adverse reactions
1. Subcutaneous amivantamab combined with lazertinib was non-inferior to intravenous amivantamab...
Read More
Amivantamab and Lazertinib in Untreated EGFR-Mutated Advanced NSCLC
1. The progression-free survival between the amivantamab–lazertinib group (23.7 months) and the...
Read More
Anti-CD38 monoclonal antibody improves platelet counts in immune thrombocytopenia
1. In this randomized controlled trial, CM313, an anti-CD38 monoclonal antibody therapy, was...
Read More
APOE3 Christchurch heterozygosity may delay cognitive impairment in Alzheimer’s disease
1. Carriers of the E280A variant of presenilin 1 (PSEN1E280A) who were heterozygous for the...
Read More
Daratumumab linked to improved progression-free survival and MRD-negativity in transplant-eligible myeloma patients
1. Daratumumab in combination with bortezomib, thalidomide, and dexamethasone (D-VTd) as induction...
Read More
Circulating Tumor DNA-Guided De-Escalation Targeted Therapy for Advanced NSCLC
1. Patients with no biochemical or radiographic evidence of progressive disease had a median...
Read More
Ticagrelor and aspiring dual antiplatelet therapy is favourable over monotherapy following coronary artery bypass
1. Dual antiplatelet therapy with ticagrelor and asprin led to a significantly lower risk of major...
Read More