chronic-disease

Torsemide not associated with significant difference in all-cause mortality over 12 months compared to furosemide – The TRANSFORM-HF randomized clinical trial

Jan 24, 2023

1. In this randomized clinical trial, among 2859 patients, death occurred in 26.1% of patients...

Machine-learning based prompts for serious illness conversations reduces end of life systemic therapy use

Jan 24, 2023

1. The proportion of patients receiving serious illness conversations (SICs) was increased in the...

Intranasal corticosteroids no better than saline in treating pediatric sleep-disordered breathing

Jan 24, 2023

1. In a randomized controlled trial of children with sleep-disordered breathings, intranasal...

Futibatinib for FGFR2 Mutated Intrahepatic Cholangiocarcinoma

Jan 24, 2023

1. Using futibatinib to treat patients with FGFR mutated intrahepatic cholangiocarcinoma resulted...

Combined visual-olfactory training for COVID-19 resultant olfactory loss

Jan 24, 2023

1. Participants with post-viral olfactory dysfunction (PVOD) who underwent olfactory training (OT)...

Time-restricted eating ineffective for weight loss

Jan 24, 2023

1. Time-restricted eating was not an effective strategy for long-term weight loss in a general...

Prevalence, awareness, treatment, and control of hypertension in China

Jan 20, 2023

1. In this national survey study, the prevalence of hypertension significantly increased from 2004...

Metformin use in Type 2 Diabetes associated with decreased risk of joint replacement

Jan 18, 2023

1. For patients with type 2 diabetes mellitus (T2DM), metformin use was associated with a...

High-dose selenium not associated with a reduction in morbidity and mortality in high-risk cardiac surgery patients

Jan 18, 2023

1. In this randomized clinical trial of 1416 adult cardiac surgery patients, high-dose selenium...

Adagrasib provides antitumour activity against KRAS G12C mutant metastatic colorectal cancer both as monotherapy and in combination with cetuximab

Jan 18, 2023

1. Overall tumour response to monotherapy treatment with adagrasib was 23% 46% in combination with...

Adding posterior wall isolation to pulmonary vein isolation not beneficial in ablation for patients with persistent atrial fibrillation — the CAPLA trial

Jan 18, 2023

1. Among patients with persistent atrial fibrillation (AF) treated with cardiac ablation, those...

Cisplatin with Veliparib in BRCA Stratified Metastatic Triple-Negative Breast Cancer

Jan 18, 2023

1. There was some progression-free survival benefit in adding veliparib to cisplatin in patients...

Physical activity may be helpful in treating depressive symptoms in children and adolescents

Jan 18, 2023

1. In a systematic review and meta-analysis, physical activity interventions were shown to...

Web-based self-treatment may be an effective strategy in the management of benign paroxysmal positional vertigo

Jan 18, 2023

1. 85% of individuals randomized to undergo treatment with a web-based self-directed regimen were...

Anterior knee pain following ACL reconstruction

Jan 15, 2023

1. Anterior knee pain (AKP) is a potential complication of ACL Reconstruction (ACLR) with...

Ecopipam reduces tics in children with Tourette syndrome

Jan 14, 2023

1. In a phase 2 trial of patients with Tourette syndrome, ecopipam, a selective dopamine receptor...

Post-acute care program for frail geriatric patients associated with better post-discharge outcomes

Jan 14, 2023

1. Frail, elderly patients participating in a post-acute care (PAC) program for more than 2 weeks...

Chronic pain conditions associated with increased risk of later suicidal behaviour

Jan 13, 2023

1. Experiencing general chronic pain or somatic chronic pain are associated with increased risk of...

Clinical decision-making strategy improves acute heart failure outcomes

Jan 12, 2023

1. A hospital-based strategy to support clinical decision-making and rapid follow-up resulted in a...

Frail patients with acute decompensated heart failure may benefit from physical rehabilitation intervention

Jan 12, 2023

1. Patients with acute heart failure who were more frail at baseline derived greater benefits from...

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chronic-disease