Adagrasib in Advanced Solid Tumors Harboring a KRASG12C Mutation
Bookmark1. The overall objective response rate was 35.1% in patients with initial measurable...
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chronic-disease
Sound and light interventions improve sleep in critically ill patients
Bookmark1. In this systematic review and meta-analysis, it was found that among critically ill...
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Cesarean delivery may be associated with increase odds of developing early-onset colorectal cancer in women
Bookmark1. In a case-control study based in Sweden, females born by C-section had greater odds of...
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Physical activity interventions may improve symptom resolution in children following concussion
1. In a systematic review and meta-analysis of interventions following concussion in children,...
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Bempedoic acid reduces the risk of major adverse cardiovascular events
1. In this randomized controlled trial, bempedoic acid significantly reduced low-density...
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Sotatercept improves outcomes in patients with pulmonary arterial hypertension
1. Among patients on stable therapy for pulmonary arterial hypertension (PAH), sotatercept...
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The Medical Outcomes Short Form 12 questionnaire is often used in patients with type 2 diabetes
1. In this systematic review, the most common validated questionnaire used to evaluate the quality...
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Dersimelagon reduces symptomatic disease in erythropoietic protoporphyrias
1. In this randomized controlled trial, oral dersimelagon resulted in significantly increased time...
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Stereotactic radiosurgery did not outperform conventional external beam radiotherapy in patients with localized vertebral metastatic lesions
1. Pain response at 3 months post-treatment show no advantage of stereotactic radiosurgery vs....
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Long-Term Outcomes of Sotorasib in KRAS-G12C Non–Small-Cell Lung Cancer
1. Sotorasib showed prolonged efficacy with a median OS of 12.5 months (33% at 24 months) and an...
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Donor sex has no effect on survival in patients receiving red blood cell transfusions
1. In this randomized controlled trial, donor sex did not result in a significant difference in...
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ECZTRA 6 Phase 3 Randomized Trial Supports Tralokinumab for Adolescent Moderate-to-Severe Atopic Dermatitis
1. Interleukin-13 targeted treatment with tralokinumab was effective and well-tolerated for...
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C-reactive protein may have superior prognostic value compared to low-density lipoprotein cholesterol for patients on statin therapy
1. High-sensitivity C-reactive protein increased the risk of all-cause mortality by two- to...
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Maternal lithium exposure in drinking water may increase risk of autism in offspring
1. In a population-based case-control study in Denmark, maternal exposure to lithium in water...
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Migraines associated with increased iron deposition in various brain structures
1. Patients with migraines had increased iron deposition in the putamen, caudate, and nucleus...
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Intradialytic exercise may improve patient survival rates in patients receiving hemodialysis
1. Intradialytic exercise for a minimum of 60 minutes during thrice weekly dialysis sessions...
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C-reactive protein may have superior prognostic value compared to LDL-cholesterol for patients on statin therapy
1. High-sensitivity CRP increased the risk of all-cause mortality by two- to three-fold among all...
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Relationship between mean blood pressure and clinical outcome after acute ischemic stroke
1. This retrospective cohort study found a U-shaped relationship between mean SBP and 3-month...
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Yoga helps alleviate symptoms of mild to moderate asthma in adults
1. In this meta-analysis, asthma patients who used yoga breathing exercises reported better...
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Early antibiotics in noncritical premature infants without clear infection linked to adverse outcomes
1. In a prospective cohort study, early antibiotic use in preterm, non-critical infants without a...
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