Atezolizumab, Vemurafenib, and Cobimetinib in Melanoma With CNS Metastases
Bookmark1. Intracranial objective response rate was 42% in the BRAF V600 mutation-positive cohort...
Read More
chronic-disease
Computer-aided detection does not improve neoplasm detection with colonoscopy
Bookmark1. The GI-Genius neural network system did not improve the rate of detecting advanced...
Read More
Younger onset of non-alcoholic fatty liver disease associated with greater cancer risk
Bookmark1. In this case-control study, younger age of onset of non-alcoholic fatty liver disease...
Read More
Bundled parenting and nutrition outreach program may positively influence the developmental and nutritional outcomes of siblings of targeted children
Bookmark1. Siblings of children receiving bundled parenting and nutrition intervention had better...
Read More
Complete revascularization reduces mortality in older adults with myocardial infarction
Bookmark1. In this randomized controlled trial, complete revascularization reduced the risk of...
Read More
Nurse-delivered sleep restriction therapy effective for treatment of chronic insomnia
Bookmark1. Sleep restriction therapy was superior to sleep hygiene for the management of chronic...
Read More
Association between changes in carbohydrate intake and long term weight changes
Bookmark1. In this prospective cohort study, the types of carbohydrates consumed were associated...
Read More
Increased consumption of ultra-processed foods may be associated with higher mortality in diabetic patients
Bookmark1. In this prospective cohort study, greater ultra-processed food intake was associated...
Read More
Intravenous thrombolysis plus endovascular treatment may be more efficacious for acute ischemic stroke
Bookmark1. The 90-day modified Ranking Scale score was comparable for patients in intravenous...
Read More
Pilot program of chronic hepatitis B treatment in Ethiopia
Bookmark1. In this pilot program conducted in Ethiopia, researchers demonstrated the long-term...
Read More
Supplementation with γ-aminobutyric acid does not improve glucose control in patients with prediabetes
Bookmark1. In this randomized controlled trial, long-term γ-aminobutyric acid (GABA)...
Read More
Prophylactic Radiation Therapy for High-Risk Asymptomatic Bone Metastases
Bookmark1. The hazard ratio of skeletal-related events in patients treated with radiation compared...
Read More
Omission of axilla surgery is non-inferior to sentinel lymph node biopsy in female patients with small breast cancers and clinically negative axillary lymph nodes
Bookmark1. 5-year distant disease-free survival was comparable between both groups. 2. 5-year...
Read More
Glucagon-like peptide-1 receptor agonists exhibit weight loss effects in non-diabetic patients with obesity
Bookmark1. This systematic review found that non-diabetic patients with obesity who received...
Read More
Budesonide may be effective for slowing renal function decline in patients with IgA nephropathy
Bookmark1. Reduction in time-weighted glomerular filtration rate (GFR) decline was significantly...
Read More
Intravenous dihydroergotamine safe for refractory chronic migraine
Bookmark1. Intravenous dihydroergotamine (DHE) was found in this retrospective study to be an...
Read More
Immunotherapy plus stereotactic radiotherapy improves outcomes in early-stage lung cancer
Bookmark1. 4-year event-free survival was significantly greater in I-SABR (77%) versus SABR alone...
Read More
Severe premenstrual disorder may increase risk of early onset perimenopausal symptoms
Bookmark1. This prospective study found that women with severe premenstrual disorders (PMDs) were...
Read More
Tumor Treating Fields vs Standard Therapy in Treatment-Resistant Metastatic NSCLC
Bookmark1. The median OS was 13.2 months with TTFields arm vs 9.9 months with standard arm, with...
Read More
Cognitive behavioural therapy effective for fibromyalgia pain
Bookmark1. This randomized controlled trial found that an 8-week cognitive behavioural therapy...
Read More